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Most people are familiar with ultrasound as a diagnostic tool. Now ExAblate® 2000, a Magnetic Resonance guided Focused Ultrasound system, unleashes the therapeutic potential of ultrasound by integrating it with the precision guidance and monitoring provided by MR imaging.

• ExAblate is a Magnetic Resonance guided Focused Ultrasound system which uses a magnetic resonance imaging (MRI) scanner to identify tissues in the body and plan the treatment. During the procedure, delivery of Focused Ultrasound energy is guided and controlled using MR thermal imaging.
• Thermal imaging feedback allows the physician to monitor and adjust the treatment to ensure that:
  • the targeted tumor is fully treated
  • all other tissue is avoided
• Works with the GE 1.5 Tesla MRI system
• Awarded the CE Mark and ISO 9001 certification in 2002
• 2004 grand prize winner of European Union's IST award for innovation and potential to benefit mankind

Benefits of ExAblate

• Non-invasive, no incision required, no anesthesia
• Low rate of complications
• Return to normal activity within one to two days
• Outpatient procedure - no hospital stay

How It Works

• MR image allows physician to locate diseased tissue or tumor
• Ultrasound energy is focused to a small volume within the tumor
• Heat of intense ultrasound waves destroys tissue
• Process is repeated as many times as necessary until tumor is destroyed
• Body disposes of destroyed tissue as part of normal function

FDA Approval
In October 2004, the FDA approved the ExAblate system for treatment of symptomatic uterine fibroids. The FDA approval followed regulatory approvals in Europe in 2002. The system also is in use in Japan.

Future Applications

• Breast fibroadenoma
• Breast cancer
• Brain tumors
• Liver
• Bone
• Prostate
• Others

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